1-(1H-Indol-3-yl)acetone

  • 2-Propanone, 1-(1H-indol-3-yl)
  • 3-Acetonylindole
  • 3-(2-Oxopropyl)indole
  • Indole-3-acetone
  • Indol-3-yl-2-propanone
  • 3-Indolylacetone
Formula
C11H11NO
Structure
Description
Tan solid.

Registry Numbers and Inventories.
CAS
1201-26-9
EC (EINECS/ELINCS)
214-855-4
Merck
13,4989

Properties.
Formula
C11H11NO
Formula mass
173.21
Melting point, °C
118 - 119
Boiling point, °C
342
Vapor pressure, mmHg
7.9E-5 (25 C)
Density
1.167 g/cm3 (20 C)
Solubility in water
1.2 g/L
pKa/pKb
16.67 (pKa)
Partition coefficient, pKow
1.36
Heat of vaporization
58.53 kJ/mol

Hazards and Protection.
Storage
Store at 2 - 8 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Oxides of carbon and nitrogen.

Fire.
Flash Point,°C
168
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
May be harmful by inhalation, ingestion, or skin absorption.
   Skin
May cause irritation.
   Eyes
May cause irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.