1-Aminoglycerol

  • 2,3-Dihydroxypropylamine
  • 3-Amino-1,2-propanediol
  • 1-Amino-2,3-dihydroxypropane
  • Isoserinol
Formula
NH2CH2CH(OH)CH2OH
Structure
Description
Viscous, colorless liquid.

Registry Numbers and Inventories.
CAS
616-30-8
EC (EINECS/ELINCS)
210-475-8
S 26 36/37/39 45
RTECS
TY2800000
RTECS class
Other
UN (DOT)
2735
Beilstein/Gmelin
1719121
Beilstein Reference
4-04-00-01865
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H9NO2
Formula mass
91.11
Boiling point, °C
264
Vapor pressure, mmHg
0.075 (20 C)
Density
1.1752 g/cm3 (20 C)
Solubility in water
Very soluble
Viscosity
4300 cP @ 20 C
Refractive index
1.49 (10 C)
pKa/pKb
5.56 pKb

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Moisture, strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
186
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2735
Response guide
HS Code
2922 19 80