1-Bromo-2-nitrobenzene

  • Benzene, 1-bromo-2-nitro-
  • 2-Bromo-1-nitrobenzene
  • o-Bromonitrobenzene
  • o-Nitrobromobenzene
  • o-Nitrophenyl bromide
Formula
1-(Br)-2-(NO2)C6H4
Structure
Description
Yellow solid.

Registry Numbers and Inventories.
CAS
577-19-5
EC (EINECS/ELINCS)
209-409-0
R 20/21/22 33 36/38
S 26 36/37/39
RTECS
CY9040450
RTECS class
Mutagen
UN (DOT)
2732
Beilstein/Gmelin
2044109
Beilstein Reference
4-05-00-00728
Canada DSL/NDSL
NDSL
US TSCA
Listed
New Zealand
Listed

Properties.
Formula
C6H4BrNO2
Formula mass
202.01
Melting point, °C
39 - 42
Boiling point, °C
261
Density
1.62 g/cm3 (20 C)
Solubility in water
Insoluble
Surface tension
43.44 g/s2 (56 C)

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong bases, strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, bromine.

Fire.
Flash Point,°C
112
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Containers may explode when heated.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed. Laboratory experiments have resulted in mutagenic effects.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Effects may be delayed 2 to 4 hours. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood.
   Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.
   Skin
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be absorbed through the skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2732
Response guide
Hazard class
6.1
Packing Group
III
 
HS Code
2904 90 85