1-Bromo-3,5-bis(trifluoromethyl)benzene

  • Benzene, 1-bromo-3,5-bis(trifluoromethyl)-
Formula
C8H3BrF6
Structure
Description
Pale-yellow liquid.

Registry Numbers and Inventories.
CAS
328-70-1
EC (EINECS/ELINCS)
206-334-5
EC Class
irritant
R 36/38
Beilstein/Gmelin
2123669
Beilstein Reference
4-05-00-00946
New Zealand
Listed

Properties.
Formula
C8H3BrF6
Formula mass
293.00
Melting point, °C
-16
Boiling point, °C
152 - 155
Vapor pressure, mmHg
4 (25 C)
Density
1.7048 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.43 (20 C)
Partition coefficient, pKow
4.73
Heat of vaporization
37.5 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide, hydrogen fluoride, hydrogen bromide.

Fire.
Flash Point,°C
40
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
Chronic inhalation and ingestion may cause fluorosis with skeletal abnormalities. Chronic exposure to fluoride compounds may cause systemic toxicity.
   Ingestion
The toxicological properties of this substance have not been fully investigated. Exposure to fluoride compounds can result in systemic toxic effects on the heart, liver, and kidneys. It may also deplete calcium levels in the body leading to hypocalcemia and death.
   Inhalation
The toxicological properties of this substance have not been fully investigated.
   Skin
No information regarding skin irritation and other potential effects was found.
   Eyes
No information regarding eye irritation and other potential effects was found.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2903 69 90