1-Fluoro-4-nitrobenzene

  • 4-Fluoronitrobenzene
  • 4-Fluoro-1-nitrobenzene
  • p-Nitrofluorobenzene
  • 1-Nitro-4-fluorobenzene
Formula
1-(F)C6H4-4-(NO2)
Structure
Description
Yellow needles.
Uses
A component of hair dyes.

Registry Numbers and Inventories.
CAS
350-46-9
EC (EINECS/ELINCS)
206-502-8
EC Class
harmful, irritant
R 20 24/25 33 36/38
S 26 28 36/37/39 45
RTECS
DA1400000
RTECS class
Agricultural Chemical and Pesticide; Mutagen
UN (DOT)
2810
Beilstein/Gmelin
606923
Beilstein Reference
4-05-00-00719
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6H4FNO2
Formula mass
141.10
Melting point, °C
21
Boiling point, °C
205
Vapor pressure, mmHg
0.41 (25 C)
Density
1.326 g/cm3
Solubility in water
Insoluble
Viscosity
2.25 cp (30 C)
Refractive index
1.5316 (20 C)
Partition coefficient, pKow
1.82
Heat of vaporization
42.1 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Wash area with soap and water. Remove all sources of ignition. Provide ventilation.
Disposal code
2
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong bases.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, fluoride fumes.

Fire.
Flash Point,°C
83
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Combustible Liquid. Containers may explode when heated. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Laboratory experiments have resulted in mutagenic effects.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Causes effects similar to those of acute skin absorption. Effects may be delayed 2 to 4 hours.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation. May be absorbed through the skin. Absorption into the body may cause cyanosis. Effects may be delayed.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2810
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
HS Code
2904 90 85