1-Methoxy-2-propanol

  • Propylene glycol, monomethyl ether
  • 1-Methoxy-propane-2-ol
  • 1-Methoxy-2-hydroxypropane
Formula
C4H10O2
Structure
Description
Clear colorless liquid with ether-like odor, lachrymator, hygroscopic.
Uses
Chiefly used in manufacture of lacquers & paints.

Registry Numbers and Inventories.
CAS
107-98-2
EC (EINECS/ELINCS)
203-539-1
EC Index Number
603-064-00-3
EC Class
Flammable
RTECS
UB7700000
RTECS class
Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
3092
Beilstein/Gmelin
1731270
Beilstein Reference
3-01-00-02146
Swiss Giftliste 1
G-2805
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H10O2
Formula mass
90.12
Melting point, °C
-97
Boiling point, °C
119.6
Vapor pressure, mmHg
12
Vapor density (air=1)
> 1
Saturation Concentration
About 1.5% (15000 ppm) at 25 C (calculated)
Evaporization number
About 0.7 (butyl acetate = 1)
Critical temperature
307
Critical pressure
40.59
Density
0.9335 g/cm3 (15 C)
Solubility in water
Miscible
Viscosity
1.67 cp (25 C)
Surface tension
27.7 g/s2
Refractive index
1.4034 (20 C)
Heat of vaporization
32.6 kJ/mol
Heat of combustion
-2324 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Keep containers tightly closed.
B2 D2B
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. A vapor suppressing foam may be used to reduce vapors.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
31
Autoignition, °C
287
Upper exp. limit, %
13.8
Lower exp. limit, %
1.6
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
FLAMMABLE.
Hazards
Flashback along vapor trail may occur. Vapor may explode if ignited in an enclosed area.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
0
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 100 ppm; 369 mg/m3 (as TWA); 150 ppm; 553 mg/m3 (STEL) (ACGIH 1997). MAK: 100 ppm; 375 mg/m3; (1996) NIOSH REL: TWA 100 ppm (360 mg/m3) ST 150 ppm (540 mg/m3)
Poison_Class
-
Exposure effects
Repeated or prolonged exposure may cause CNS stimulation.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
   Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. Vapors may cause dizziness or suffocation.
   Skin
May cause skin irritation. Prolonged and/or frequent contact may cause drying, cracking or folliculitis.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
3092
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
PME
 
40 Glycol ethers
HS Code
2909 49 19
 
Std. Transport #
4909309
 
IMO Chemical Code
18
IMO Pollution Category
D