1-Phenylpiperazine

  • N-Phenylpiperazine
  • NPP
Formula
C10H14N2
Structure
Description
Clear colorless to light yellow liquid.

Registry Numbers and Inventories.
CAS
92-54-6
EC (EINECS/ELINCS)
202-165-6
EC Class
toxic, corrosive
R 22 24 34
S 26 28 36/37/39 45
RTECS
TM2625000
RTECS class
Mutagen; Primary Irritant
UN (DOT)
2927
Beilstein/Gmelin
132157
Beilstein Reference
5-23-01-00160
Swiss Giftliste 1
G-3897
Canada DSL/NDSL
DSL
US TSCA
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C10H14N2
Formula mass
162.24
Melting point, °C
17 - 19
Boiling point, °C
286
Density
1.0725 g/cm3 (14 C)
Solubility in water
Very soluble
Refractive index
1.5844 (16.8 C)
pKa/pKb
5.06 (pKb)

Hazards and Protection.
Storage
Keep containers tightly closed. Store in a cool, dry area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
140
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Poison_Class
3
Exposure effects
   Ingestion
Harmful if swallowed. Causes gastrointestinal tract irritation.
   Inhalation
Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Inhalation may produce burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. Causes irritation of the mucous membrane and upper respiratory tract.
   Skin
May be fatal if absorbed through the skin. Causes severe skin irritation and possible burns. Substance is readily absorbed through the skin.
   Eyes
Causes severe eye irritation and possible burns. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.
UN number
2927
Response guide
HS Code
2933 59 95