1-Piperazineethanol

  • N-(2-Hydroxyethyl)piperazine
Formula
C6H14N2O
Structure
Description
Clear, light yellow liquid.

Registry Numbers and Inventories.
CAS
103-76-4
EC (EINECS/ELINCS)
203-142-3
EC Class
irritant
R 38 41
S 26 37/39
RTECS
TL6825000
RTECS class
Primary Irritant
Beilstein/Gmelin
104361
Beilstein Reference
5-23-01-00406
Swiss Giftliste 1
G-3843
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H14N2O
Formula mass
130.19
Melting point, °C
-38
Boiling point, °C
246
Vapor pressure, mmHg
0.005 (25 C)
Vapor density (air=1)
4.5
Density
1.0595 g/cm3 (20 C)
Solubility in water
Very soluble
Refractive index
1.5058 (20 C)
pKa/pKb
4.73 (pKb)
Partition coefficient, pKow
-0.45
Heat of vaporization
56.0 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Disposal code
5
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, acids, chlorinated solvents, copper, copper alloys.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
102
Autoignition, °C
280
Upper exp. limit, %
8.9
Lower exp. limit, %
1.4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
The toxicological properties of this substance have not been fully investigated.
   Ingestion
Ingestion of large amounts may cause gastrointestinal irritation. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
May cause respiratory tract irritation.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2933 59 95