1-Pyrrolidineacetamide, N-(2,6-dimethylphenyl)-2-oxo

  • N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide
  • DM-9384
  • DMPPA
  • Nefiracetam
  • 2-Oxo-1-pyrrolidinylacetic acid,-2,6-dimethylanilide
  • Translon
Formula
C14H18N2O2
Structure
Description
White solid.

Registry Numbers and Inventories.
CAS
77191-36-7
RTECS
UX9655650
Merck
12,6528
Beilstein/Gmelin
6848330

Properties.
Formula
C14H18N2O2
Formula mass
246.31
Melting point, °C
153
Boiling point, °C
459
Vapor pressure, mmHg
1.4E-8 (25 C)
Density
1.19 g/cm3 (20 C)
Solubility in water
0.39 g/L (25 C)
pKa/pKb
12.24 (pKb)
Partition coefficient, pKow
1.53
Heat of vaporization
71.88 kJ/mol

Hazards and Protection.
Storage
Keep container tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide, and nitrogen oxides.

Fire.
Flash Point,°C
231
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
Harmful if swallowed.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
   Skin
May cause irritation. May be harmful if absorbed through the skin.
   Eyes
May cause irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.