1,1-Diphenylhydrazine

  • alpha,alpha-Diphenylhydrazine
  • N,N-diphenylhydrazine
  • Hydrozobenzene
Formula
(C6H5)2NNH2
Structure
Description
Yellow crystals.
Uses
As reagent for arabinose & lactose 1,1-diphenylhydrazine hydrochloride.

Registry Numbers and Inventories.
CAS
530-50-7
EC (EINECS/ELINCS)
208-483-1
RTECS
MV3450000
RTECS class
Mutagen
Merck
12,3384
Beilstein/Gmelin
957349
Beilstein Reference
4-15-00-00055

Properties.
Formula
C12H12N2
Formula mass
184.24
Melting point, °C
34.5
Boiling point, °C
330
Vapor pressure, mmHg
0.0002 (25 C)
Odor Threshold Odor threshold 1-10 ppm
Density
1.19 g/cm3 (16 C)
Solubility in water
Insoluble
Refractive index
1.649 (20 C)
pKa/pKb
10.66 (pKb)
Partition coefficient, pKow
2.80
Heat of vaporization
57.3 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Organic vapor acid gas canister is used.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Flash Point,°C
181
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure effects
CNS stimulation and seizures have occurred after absorption by any route.
   Ingestion
Anorexia and vomiting are common symptoms.
   Inhalation
Acute exposure to low concentrations of hydrazines may cause delayed death (days) and produce bronchial mucous destruction and pulmonary edema.
   Skin
Hydrazine may cause strong skin irritation.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.