1,1,1,3,3,3-Hexafluoro-2-propanol

  • 2-Propanol, 1,1,1,3,3,3-hexafluoro-
  • 1,1,1,3,3,3-Hexafluoro-2-hydroxypropane
  • 1,1,1,3,3,3-Hexafluoroisopropyl alcohol
  • 2,2,2-Trifluoro-1-(trifluoromethyl)ethanol
  • Bis(trifluoromethyl)methanol
  • Hexafluoroisopropyl alcohol
Formula
CF3CH(OH)CF3
Structure
Description
A light colored liquid.

Registry Numbers and Inventories.
CAS
920-66-1
EC (EINECS/ELINCS)
213-059-4
EC Class
harmful, corrosive
R 20/22 34 41
S 26 36/37/39 45
RTECS
UB6450000
RTECS class
Other
UN (DOT)
3265
Beilstein/Gmelin
3624201
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H2F6O
Formula mass
168.04
Melting point, °C
-96
Boiling point, °C
59.1
Vapor pressure, mmHg
158 (25 C)
Vapor density (air=1)
5.8
Evaporization number
100 (butyl acetate=1)
Critical temperature
149
Critical pressure
36.8
Density
1.492 g/cm3
Solubility in water
Insoluble
Viscosity
1.65 mPas
Refractive index
1.27 (20 C)
pKa/pKb
9.75 (pKa)
Partition coefficient, pKow
1.91
Heat of vaporization
59.0 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Use only in a chemical fume hood.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Disposal code
2
Stability
Has not been fully evaluated.
Incompatibilities
Strong acids, acid chlorides, oxidizing agents, aluminium, zinc, strong bases.
Decomposition
Carbon monoxide, carbon dioxide, hydrogen fluoride.

Fire.
Flash Point,°C
-2
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Substance is noncombustible. Extinguishing media: Use extinguishing media most appropriate for the surrounding fire.
Fire potential
This chemical is probably combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
May cause liver and kidney damage.
   Ingestion
May cause central nervous system depression, kidney damage, and liver damage. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation. May cause effects similar to those described for ingestion.
   Skin
Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May cause irritation with pain and stinging, especially if the skin is abraded.
   Eyes
Causes eye irritation. May cause eye injury.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
3265
Response guide
Hazard class
8
Packing Group
I; II; III
 
HS Code
2905 59 10
 
Std. Transport #
4936538