1,2-Butanediol

  • 1,2-Butylene glycol
  • 1,2-Dihydroxybutane
  • Butane-1,2-diol
Formula
C4H10O2
Structure
Description
Clear, colorless, viscous liquid.
Uses
In indust as intermediate in polyester resins.

Registry Numbers and Inventories.
CAS
584-03-2
EC (EINECS/ELINCS)
209-527-2
RTECS
EK0380000
RTECS class
Other
Beilstein/Gmelin
969169
Beilstein Reference
4-01-00-02507
Swiss Giftliste 1
G-1314
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H10O2
Formula mass
90.14
Melting point, °C
-50
Boiling point, °C
193
Vapor pressure, mmHg
0.08
Vapor density (air=1)
3.1
Critical temperature
407
Critical pressure
51.42
Density
1.0189 g/cm3 (0 C)
Solubility in water
Very soluble
Viscosity
106.00 cp (10.45 C)
Surface tension
31.2 g/s2 (25 C)
Refractive index
1.4391 (18 C)
Heat of vaporization
48.26 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate safety goggles, protective clothing and gloves.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Above 90 C, explosive vapor/air mixtures may be formed.
Incompatibilities
Reacts with strong oxidizers. Avoid contact with acid chlorides, acid anhydrides, chloroformates and reducing agents.
Decomposition
When heated to decomposition it emits acrid smoke and irritating fumes.

Fire.
Flash Point,°C
90
Autoignition, °C
390
Upper exp. limit, %
13.5
Lower exp. limit, %
2.4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
Moderate fire hazard, when exposed to heat or flame.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
-
Exposure effects
Abnormally low blood pressure or elevated blood pressure may occur as a result of glycol toxicity. Rapid breathing has been reported with ethylene glycol and glycol ether ingestions. CNS depression, seizures, coma, cerebral edema, and delayed neurologic sequelae may occur following most glycol exposures. CNS symptoms are common following exposures to most glycols. Exposures to glycols have resulted in teratogenicity, specifically craniofacial and neural tube closure defects and skeletal dysplasia in animal studies.
   Ingestion
Nausea and vomiting are frequent early findings.
   Inhalation
Tachypnea, respiratory irritation, and pulmonary edema have been reported following exposure to glycols.
   Skin
May cause irritation.
   Eyes
Eye irritation may occur with any of the glycols.

First aid
 
   Ingestion
Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower lids.

Transport.
20 Alcohols, Glycols