1,2-Butylene oxide

  • 1,2-Epoxybutane
  • 1-Butene oxide
  • Ethyloxirane
Formula
C4H8O
Structure
Description
Clear, colorless liquid, pungent, sweetish odor, somewhat like butyric acid.
Uses
Intermediate, for various polymers, stabilizer for chlorinated solvents.

Registry Numbers and Inventories.
CAS
106-88-7
EC (EINECS/ELINCS)
203-438-2
EC Index Number
603-102-00-9
EC Class
Highly flammable; Carcinogenic Category 3; Harmful; Irritant; Dangerous for the Environment
R 11 20/21/22 36/37/38 40 52/53
S 9 16 29 36/37 61
RTECS
EK3675000
RTECS class
Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
3022
Beilstein/Gmelin
102411
Beilstein Reference
5-17-01-00056
Swiss Giftliste 1
G-3649
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H8O
Formula mass
72.11
Melting point, °C
-130
Boiling point, °C
63
Vapor pressure, mmHg
150 (21 C)
Vapor density (air=1)
2.49
Saturation Concentration
19% at 20 C (calculated)
Critical temperature
243
Critical pressure
41.36
Density
0.8345 g/cm3 (18 C)
Solubility in water
95 g/L
Refractive index
1.385 (18 C)
Partition coefficient, pKow
0.64
Heat of vaporization
29.3 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated location. Store away from heat, oxidizing materials, and sunlight. Storage location should be close to laboratory where it is to be used, so that only small amounts need to be transported. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.
Handling
Containers of this material may be hazardous when emptied. Since emptied containers retain product residues (vapor, liquid, and/or solid), all hazard precautions given in the data sheet must be observed.
Protection
Wear appropriate chemical protective clothing.
Respirators
Wear positive pressure self-contained breathing apparatus.
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to disperse vapors and dilute standing pools of liquid. Apply water spray or mist to knock down vapors. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. Apply universal gelling agent to immobilize spill. Water spill: Use natural barriers or oil spill control booms to limit spill travel. Use surface active agent (e.g. detergent, soaps, alcohols), if approved by EPA. Inject universal gelling agent to solidify encircled spill and increase effectiveness of booms.
Stability
Polymerizes easily.
Incompatibilities
React with acids, bases, and oxidizing and reducing agents.
Decomposition
When heated to decomposition it emits acrid smoke and fumes.

Fire.
Flash Point,°C
-26
Autoignition, °C
370
Upper exp. limit, %
25.1
Lower exp. limit, %
1.3
Fire fighting
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use alcohol foam, dry chemical or carbon dioxide.
Fire potential
HIGHLY FLAMMABLE.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases. Extinguishing of flames allows for the generation of explosive vapors.
Health
3
 
Flammability
3
 
 
Reactivity
2
 
 
Special
W

Health.
Carcinogin
I-2B
Poison_Class
4
Exposure effects
Mild central nervous system depression or excitation may occur after ingestion or vapor inhalation. CNS effects can occur secondary to hydrocarbon pneumonitis and hypoxia, or from additives and contaminants (aniline, heavy metals, camphor, or pesticides). Some hydrocarbons are simple asphyxiants (e.G., Methane, ethane, propane gasses) which can produce CNS effects secondary to hypoxia. In a prospective study in Toronto, major congenital malformations were noted in 13 of 125 fetuses of mothers exposed to organic solvents during pregnancy.
   Ingestion
Nausea, vomiting, diarrhea, and abdominal pain may occur following ingestion.
   Inhalation
Coughing, choking, tachypnea, dyspnea, cyanosis, rales, hemoptysis, pulmonary edema, pneumatoceles, lipoid pneumonia, or respiratory arrest may develop following ingestion and aspiration.
   Skin
Redness.
   Eyes
Redness, pain.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. Volatile chemicals have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
3022
Response guide
Hazard class
3
Packing Group
II
 
USCG CHRIS Code
BTO
 
16 Alkylene oxides
HS Code
2910 90 00
 
Std. Transport #
4908144
 
IMO Pollution Category
C
IMO Hazard code
S/P