1,2-Dichloro-4-isocyanatobenzene

  • 3,4-Dichlorophenyl isocyanate
Formula
3,4-(Cl)2C6H3NCO
Structure
Description
White to yellow crystalline solid with an irritating odor, lachrymator.
Uses
Chemical intermediate, organic synthesis.

Registry Numbers and Inventories.
CAS
102-36-3
EC (EINECS/ELINCS)
203-026-2
EC Class
toxic, irritant, sensitizing
R 23/25 36/37/38 42
S 22 26 36/37/39 45
RTECS
NQ8760000
RTECS class
Other
UN (DOT)
2250
Beilstein/Gmelin
608325
Beilstein Reference
3-12-00-01405
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C7H3Cl2NO
Formula mass
188.01
Melting point, °C
38 - 41
Boiling point, °C
234
Vapor pressure, mmHg
0.06 (25 C)
Saturation Concentration
263 ppm (0.03%) at 20 C (calculated)
Solubility in water
Insoluble
Viscosity
2x10-3 pa.s @ melting point
Partition coefficient, pKow
4.01
Heat of vaporization
47.0 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
D1A D2A D2B
Handling
Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Protection
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures. Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Incompatible with many classes of compounds, reacting exothermically to release toxic gases Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat.
Decomposition
Hydrogen chloride, hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
106
Upper exp. limit, %
8.6
Lower exp. limit, %
1.6
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Inhalation of dust is poisonous; fire may produce irritating or poisonous gases.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2250
Response guide
Hazard class
6.1
Packing Group
II
 
HS Code
2929 10 90