1,2-Diphenylhydrazine

  • N,N'-Bianiline
  • Diphenylhydrazine
  • Hydrazobenzene
Formula
C12H12N2
Structure
Description
Orange powder or a bright orange crystalline solid.
Uses
Chemical intermed for benzidine, an intermed for dyes, in synthesis of phenylbutazone (antiarthritic drug).

Registry Numbers and Inventories.
CAS
122-66-7
EC (EINECS/ELINCS)
204-563-5
EC Index Number
007-021-00-4
EC Class
Carcinogenic Category 2; Harmful; Dangerous for the Environment
RTECS
MW2625000
RTECS class
Tumorigen; Mutagen
UN (DOT)
2811
Beilstein/Gmelin
639793
Beilstein Reference
4-15-00-00056
RCRA
U109
Swiss Giftliste 1
G-5776
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C12H12N2
Formula mass
184.26
Melting point, °C
123
Boiling point, °C
309
Vapor pressure, mmHg
0.07 (25 C)
Odor Threshold Odor threshold 1-10 ppm
Density
1.158 g/cm3 (16 C)
Solubility in water
1 g/L
Partition coefficient, pKow
2.94
Heat of fusion
17.7 kJ/mol
Heat of vaporization
46.6 kJ/mol
Heat of combustion
-6695 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
88
Upper exp. limit, %
5.5
Lower exp. limit, %
0.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
This material is probably combustible.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Carcinogin
N-2, CP65
Poison_Class
1*
Exposure effects
Animal studies have reported the development of tumors.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
DPZ