1,3-Dioxane

  • 1,3-Dioxacyclohexane
  • meta-Dioxane
  • 1,3-Propanediol formal
  • Trimethylene glycol methylene ether
Formula
C4H8O2
Structure
Description
Clear colorless liquid.
Uses
Monomer for acetyl resins (no evidence of current use).

Registry Numbers and Inventories.
CAS
505-22-6
EC (EINECS/ELINCS)
208-005-1
RTECS
JG8224000
RTECS class
Mutagen
Beilstein/Gmelin
102532
Beilstein Reference
5-19-01-00011

Properties.
Formula
C4H8O2
Formula mass
88.10
Melting point, °C
-74.2
Boiling point, °C
105
Vapor pressure, mmHg
39 (25 C)
Density
1.0399 g/cm3 (15 C)
Solubility in water
Very soluble
Surface tension
33.38 g/s2 (20 C)
Refractive index
1.4165 (20 C)
Partition coefficient, pKow
-0.419
Heat of vaporization
39.1 kJ/mol
Heat of combustion
-2340 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container. Flammables-area.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition. Use a spark-proof tool.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
5
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Containers may explode in the heat of a fire. May form explosive peroxides. Forms explosive mixtures with air. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Fire potential
This chemical is flammable.

Health.
Exposure limit(s)
IDHL: NIOSH considers dioxane to be a potential occupational carcinogen.
Exposure effects
   Ingestion
Harmful if swallowed. May cause irritation of the digestive tract.
   Inhalation
Harmful if inhaled. May cause respiratory tract irritation.
   Skin
May cause skin irritation. Harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.