1,4-Butanediamine

  • Putrescine
  • 1,4-Diaminobutane
Formula
H2N(CH2)4NH2
Structure
Description
Colorless solid.
Uses
Used as a a tool in biochemical research.

Registry Numbers and Inventories.
CAS
110-60-1
EC (EINECS/ELINCS)
203-782-3
EC Class
harmful, corrosive
R 10 21/22 34
S 26 36/37/39 45
RTECS
EJ6800000
RTECS class
Mutagen; Reproductive Effector
UN (DOT)
1719
Merck
12,8134
Beilstein/Gmelin
605282
Beilstein Reference
4-04-00-01283
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H12N2
Formula mass
88.15
Melting point, °C
25 - 28
Boiling point, °C
158
Vapor pressure, mmHg
2.6 (25 C)
Vapor density (air=1)
3.0
Density
0.8704 g/cm3 (25 C)
Solubility in water
40 g/L
Refractive index
1.4969 (20 C)
pKa/pKb
3.32 (pKb)
Partition coefficient, pKow
-0.72
Heat of fusion
28.1 kJ/mol
Heat of vaporization
39.6 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.
Handling
Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
5
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
52
Upper exp. limit, %
11.2
Lower exp. limit, %
0.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
Harmful if swallowed. May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns.
   Inhalation
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract.
   Skin
Causes skin burns. May be harmful if absorbed through the skin.
   Eyes
Causes eye burns.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
1719
Response guide
Hazard class
8
Packing Group
II; III
 
7. Aliphatic amines
HS Code
2921 29 00