- 1,4-Butylene glycol
- Tetramethylene glycol
Odorless, colorless, viscous liquid.
Chemical intermediate for tetrahydrofuran, and other acetylenic chems (gamma butyrolactone), monomer for polybutylene terephthalate resins, chain extender for polyurethane resins.
Registry Numbers and Inventories.
Tumorigen; Mutagen; Human Data
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
19.5 - 20.0
Boiling point, °C
Vapor pressure, mmHg
0.01 (25 C)
Vapor density (air=1)
Odor Threshold Odor threshold Odorless.
1.017 g/cm3 (20 C)
Solubility in water
0.677 g/(cm sec) (20 C)
45.5 g/s2 (25 C)
1.446 (20 C)
31.5 (20 C)
Heat of fusion
Heat of vaporization
Heat of combustion
Hazards and Protection.
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.
Stable under normal temperatures and pressures.
Strong inorganic oxidizers, nitric acid, strong hydrogen peroxide
When heated to decomposition, emits tetrahydrofuran and carbon oxides.
Upper exp. limit, %
Lower exp. limit, %
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Water spray may cause frothing. Cool containers with flooding quantities of water until well after fire is out.
Low fire hazard, when exposed to heat or flame. Not considered to be an explosion hazard.
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Carbon dioxide and carbon monoxide may be produced in fire.
Chronic exposure may cause kidney damage.
A nonvolatile liquid - vapor inhalation is unlikely. Inhalation of high vapor concentrations may cause respiratory tract irritation and have a narcotic effect with symptoms of drunkenness.
Large oral dose may produce symptoms of narcosis, incoordination, and kidney damage.
No adverse health effects expected. Prolonged contact may cause slight irritation.
May cause mild irritation, possible reddening.
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person.
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.