1,4-Butanediol

  • 1,4-Butylene glycol
  • 1,4-Dihydroxybutane
  • Butane-1,4-diol
  • Tetramethylene glycol
Formula
HO(CH2)4OH
Structure
Description
Odorless, colorless, viscous liquid.
Uses
Chemical intermediate for tetrahydrofuran, and other acetylenic chems (gamma butyrolactone), monomer for polybutylene terephthalate resins, chain extender for polyurethane resins.

Registry Numbers and Inventories.
CAS
110-63-4
EC (EINECS/ELINCS)
203-786-5
EC Class
harmful
RTECS
EK0525000
RTECS class
Tumorigen; Mutagen; Human Data
UN (DOT)
2810
Beilstein/Gmelin
1633445
Beilstein Reference
4-01-00-02515
Swiss Giftliste 1
G-1317
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H10O2
Formula mass
90.12
Melting point, °C
19.5 - 20.0
Boiling point, °C
230
Vapor pressure, mmHg
0.01 (25 C)
Vapor density (air=1)
3.1
Odor Threshold Odor threshold Odorless.
Critical temperature
454
Critical pressure
61.39
Density
1.017 g/cm3 (20 C)
Solubility in water
Very soluble
Viscosity
0.677 g/(cm sec) (20 C)
Surface tension
45.5 g/s2 (25 C)
Refractive index
1.446 (20 C)
Dipole moment
2.4 D
Dielectric constant
31.5 (20 C)
Heat of fusion
12.0 kJ/mol
Heat of vaporization
79.30 kJ/mol
Heat of combustion
-2496 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
D2B
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong inorganic oxidizers, nitric acid, strong hydrogen peroxide
Decomposition
When heated to decomposition, emits tetrahydrofuran and carbon oxides.

Fire.
Flash Point,°C
121
Autoignition, °C
350
Upper exp. limit, %
15.3
Lower exp. limit, %
2.4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Water spray may cause frothing. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
Low fire hazard, when exposed to heat or flame. Not considered to be an explosion hazard.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Carbon dioxide and carbon monoxide may be produced in fire.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Chronic exposure may cause kidney damage.
   Ingestion
A nonvolatile liquid - vapor inhalation is unlikely. Inhalation of high vapor concentrations may cause respiratory tract irritation and have a narcotic effect with symptoms of drunkenness.
   Inhalation
Large oral dose may produce symptoms of narcosis, incoordination, and kidney damage.
   Skin
No adverse health effects expected. Prolonged contact may cause slight irritation.
   Eyes
May cause mild irritation, possible reddening.

First aid
 
   Ingestion
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2810
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
BUG
 
20 Alcohols, Glycols
HS Code
2905 39 80
 
IMO Pollution Category
D