1,4-Dioxane-[-{2L}-H8]

  • 1,4-Dioxane-2,2,3,3,5,5,6,6-d8-
Formula
[2H]8C4O2
Structure
Description
Clear, colorless liquid. Alcohol-like, ethereal odor.

Registry Numbers and Inventories.
CAS
17647-74-4
EC (EINECS/ELINCS)
241-628-7
UN (DOT)
1165
Beilstein/Gmelin
NA
New Zealand
Listed

Properties.
Formula
D8C4O2
Formula mass
96.15
Melting point, °C
11
Boiling point, °C
100
Vapor pressure, mmHg
38 (25 C)
Vapor density (air=1)
3.4
Density
1.12 g/cm3
Solubility in water
Very soluble
Viscosity
0.012cP @ 25 C
Partition coefficient, pKow
-0.27
Heat of vaporization
34.2 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. After opening, purge container with nitrogen before reclosing. Periodically test for peroxide formation on long-term storage. Addition of water or appropriate reducing materials will lessen peroxide formation. Store protected from moisture.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Use spark-proof tools and explosion proof equipment. Loosen closure cautiously before opening. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. If peroxide formation is suspected, do not open or move container. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear nitrile-latex gloves, apron, and/or clothing. Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear nitrile-latex gloves, apron, and/or clothing. Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Flush spill area with water. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Stability
Stable under normal temperatures and pressures. Prolonged exposure to air and sunlight may form unstable peroxides.
Incompatibilities
Plastics, oxidizing agents (strong, e.g. bromine, hydrogen peroxide, nitrogen dioxide, potassium nitrate), reducing agents (strong, e.g. aluminum carbide, chlorosilane, hydrogen phosphide, lithium hydride), oxygen.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
12
Autoignition, °C
180
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Can release vapors that form explosive mixtures at temperatures above the flashpoint. Use water spray to keep fire-exposed containers cool. May form explosive peroxides. Containers may explode if exposed to fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
3
 
 
Reactivity
1
 

Health.
Exposure limit(s)
20 ppm TLV {72 mg/m3}
Carcinogin
G-A3, I-2B, N-2
Exposure effects
May cause liver and kidney damage.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
   Inhalation
Effects may be delayed. Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. Inhalation of vapor may cause severe respiratory tract irritation. Olfactory fatigue may occur.
   Skin
May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1165
Response guide
Hazard class
3
Packing Group
II