1,6-Hexanediol

  • 1,6-Dihydroxyhexane
  • Hexamethylene glycol
  • Hexane-1,6-diol
Formula
HO(CH2)6OH
Structure
Description
Crystals.
Uses
Solvent, intermediate for high polymers (nylon, polyesters), coupling agent, coal coating.

Registry Numbers and Inventories.
CAS
629-11-8
EC (EINECS/ELINCS)
211-074-0
RTECS
MO2100000
RTECS class
Primary Irritant
Merck
13,4709
Beilstein/Gmelin
1633461
Beilstein Reference
4-01-00-02556
Swiss Giftliste 1
G-7744
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H14O2
Formula mass
118.18
Melting point, °C
39 - 42
Boiling point, °C
250
Vapor pressure, mmHg
0.0005
Vapor density (air=1)
4.07
Critical temperature
427
Critical pressure
29.61
Density
1.078 g/cm3 (25 C)
Solubility in water
Miscible
Viscosity
62.62 cp (39.05 C)
Refractive index
1.4579 (20 C)
Partition coefficient, pKow
-0.106
Heat of fusion
21.6 kJ/mol
Heat of vaporization
53.10 kJ/mol
Heat of combustion
-3788 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
147
Autoignition, °C
320
Upper exp. limit, %
16
Lower exp. limit, %
6.6
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Moderate when exposed to heat or flame.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Abnormally low blood pressure or elevated blood pressure may occur as a result of glycol toxicity. Rapid breathing has been reported with ethylene glycol and glycol ether ingestions. CNS depression, seizures, coma, cerebral edema, and delayed neurologic sequelae may occur following most glycol exposures. CNS symptoms are common following exposures to most glycols. Exposures to glycols have resulted in teratogenicity, specifically craniofacial and neural tube closure defects and skeletal dysplasia in animal studies.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
USCG CHRIS Code
HMG
 
20 Alcohols, Glycols
HS Code
2905 39 80
 
IMO Chemical Code
18
IMO Pollution Category
III