(1R,2S)-1-Amino-2-indanol

  • cis-(1R,2S)-1-Amino-2-indanol
  • H-Inden-2-ol, 1-amino-2,3-dihydro-, (1R,2S)-
Formula
C9H11NO
Structure
Description
White to off-white solid.

Registry Numbers and Inventories.
CAS
136030-00-7
Beilstein/Gmelin
2803742
Japan ENCS (MITI)
Listed

Properties.
Formula
C9H11NO
Formula mass
149.19
Melting point, °C
117 - 121
Boiling point, °C
291
Solubility in water
Very soluble
pKa/pKb
5.03 (pKb)
Partition coefficient, pKow
0.50

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container. Keep under a nitrogen blanket.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong acids - strong bases.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
   Ingestion
Harmful if swallowed. The toxicological properties of this substance have not been fully investigated.
   Inhalation
Harmful if inhaled. The toxicological properties of this substance have not been fully investigated.
   Skin
Harmful if absorbed through the skin. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.