2-(4-Dimethylaminostyryl)benzothiazole

  • 2-(p-(Dimethylamino)styryl)benzothiazole
  • 4-[2-(2-Benzothiazol-2-yl)vinyl]-N,N-dimethylaniline
Formula
C17H16N2S
Structure
Uses
No evidence of commercial use in U.S.

Registry Numbers and Inventories.
CAS
1628-58-6
EC (EINECS/ELINCS)
216-622-2
RTECS
DL4200000
RTECS class
Tumorigen
Beilstein/Gmelin
205731
Beilstein Reference
6-27
Swiss Giftliste 1
G-4082
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed

Properties.
Formula
C17H16N2S
Formula mass
280.41
Melting point, °C
206 - 208
Boiling point, °C
473
Vapor pressure, mmHg
4E-9 (25 C)
Solubility in water
Insoluble
pKa/pKb
9.22 (pKb)
Heat of vaporization
73.6 kJ/mol

Hazards and Protection.

Fire.
Flash Point,°C
240

Health.
Poison_Class
1*
Exposure effects
   Ingestion
Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested.
   Inhalation
Causes irritation. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases.
   Skin
Causes irritation.
   Eyes
Causes irritation.

First aid
 
   Ingestion
1. Consider gastric lavage after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Protect airway by placement in Trendelenburg and left lateral decubitus position or by endotracheal intubation. Control any seizures first. 2. Administer charcoal as a slurry 240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old. 3. Immediate dilution with milk or water may be of benefit in caustic or irritant chemical ingestions.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. Respiratory tract irritation, if severe, can progress to pulmonary edema which may be delayed in onset up to 24 to 72 hours after exposure in some cases.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.