2-Acetamidofluorene

  • N-(2-Fuorenyl)acetamide
  • N-9H-Fluorenylacetamide
  • 2-Fluorenylacetamide
  • 2-Acetylaminofluorene
  • N-Fluoren-2-ylacetamide
Formula
C15H13NO
Structure
Description
Tan, crystalline powder.
Uses
Used in the study of liver enzymes and the carcinogenicity and mutagenicity of aromatic amines as a positive control.

Registry Numbers and Inventories.
CAS
53-96-3
EC (EINECS/ELINCS)
200-188-6
RTECS
AB9450000
RTECS class
Tumorigen; Mutagen; Reproductive Effector
UN (DOT)
3143
Merck
12,4192
Beilstein/Gmelin
2807677
Beilstein Reference
4-12-00-03373
RCRA
U005
Swiss Giftliste 1
G-1037
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C15H13NO
Formula mass
223.28
Melting point, °C
190 - 193
Boiling point, °C
463
Vapor pressure, mmHg
9E-9 (25 C)
Density
1.27 g/cm3
Solubility in water
Insoluble
Partition coefficient, pKow
3.22
Heat of vaporization
72.4 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. If sweeping is necessary, use a dust suppressant agent. Avoid generating dusty conditions.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids; acid anhydrides; oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride, nitrogen.

Fire.
Flash Point,°C
277
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
This material is probably combustible.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure limit(s)
NIOSH REL: Ca See Appendix A OSHA PEL: [1910.1014] See Appendix B
Carcinogin
O, N-2, CP65
Poison_Class
1*
Exposure effects
Chronic ingestion may cause liver damage. May cause cancer in humans.
   Ingestion
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver damage.
   Inhalation
Harmful if inhaled. May cause respiratory tract irritation.
   Skin
May cause skin irritation. Harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
3143
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
AAF
 
HS Code
2924 29 95