2-Aminophenol

  • o-Aminophenol
  • 2-Hydroxyaniline
Formula
2-(NH2)C6H4OH
Structure
Description
Off-white crystals or beige powder.
Uses
Manufacture azo and sulfur dyes.

Registry Numbers and Inventories.
CAS
95-55-6
EC (EINECS/ELINCS)
202-431-1
EC Index Number
612-033-00-3
EC Class
Harmful; Mutagenic Category 3
R 20/22 68
S 28 36/37
RTECS
SJ4950000
RTECS class
Drug; Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
2512
Merck
13,460
Beilstein/Gmelin
606075
Beilstein Reference
4-13-00-00805
Swiss Giftliste 1
G-1090
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H7NO
Formula mass
109.13
Boiling point, °C
235
Vapor pressure, mmHg
0.035 (25 C)
Density
1.328 g/cm3
Solubility in water
20 g/L (20 C)
pKa/pKb
9.76 (pKa)
Partition coefficient, pKow
0.62
Heat of vaporization
49.0 kJ/mol
Heat of combustion
-3171 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up, then place into a suitable container for disposal.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, acids, acid anhydrides, acid chlorides,chloroformates.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
96
Autoignition, °C
190
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Containers may explode when heated.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
1
 
 
Reactivity
2
 

Health.
Poison_Class
3
Exposure effects
Prolonged or repeated inhalation of dusts may cause neurological damage. May cause liver and kidney damage. May cause reproductive and fetal effects.
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Exposure may cause anemia and other blood abnormalities. May be harmful if swallowed.
   Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation.
   Skin
Causes skin irritation. May cause dermatitis.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2512
Response guide
Hazard class
6.1
Packing Group
III
 
HS Code
2922 29 00