2-Butynediamide

  • Cellocidin
  • Lenamycin
  • Acetylene diamide
  • Acetylenedicarboxamide
  • Acetylenedicarboxylic acid diamide
Formula
C4H4N2O2
Structure
Description
Solid.

Registry Numbers and Inventories.
CAS
543-21-5
RTECS
AO9900000
RTECS class
Drug; Mutagen; Natural Product
Merck
12,2009
Beilstein/Gmelin
1756134
Beilstein Reference
4-02-00-02295
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C4H4N2O2
Formula mass
112.08
Melting point, °C
179
Boiling point, °C
357
Solubility in water
Very soluble
pKa/pKb
13.01 (pKa)
Partition coefficient, pKow
-1.56

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get on skin or in eyes. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Irritating and toxic fumes and gases.

Fire.
Flash Point,°C
216
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Health.
Exposure effects
   Ingestion
May be fatal if swallowed. Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation.
   Skin
Causes skin irritation. Harmful if absorbed through the skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. SPEED IS ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.