2-Chloro-4-toluidine-5-sulfonic acid

  • 4-Amino-2-chlorotoluene-5-sulfonic acid
  • 2-Amino-4-chloro-5-methylbenzenesulfonic acid
  • Brilliant Toning Red Amine
  • 2B Acid
Formula
C7H8ClNO3S
Structure
Description
Crystalline solid.
Uses
Intermediate for azo pigments.

Registry Numbers and Inventories.
CAS
88-51-7
EC (EINECS/ELINCS)
201-837-6
RTECS
XT6330000
RTECS class
Primary Irritant
Beilstein/Gmelin
2727161
Beilstein Reference
3-14-00-02216
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H8ClNO3S
Formula mass
221.67
Boiling point, °C
394
Solubility in water
Very soluble
pKa/pKb
12.17 (pKb)
Partition coefficient, pKow
1.43

Hazards and Protection.
Storage
Keep in a tightly closed container. Sore in a cool, dry location.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evaucuate area and ventilate. Wear protective equipment. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Stable.
Incompatibilities
Strong oxidizing agents.
Decomposition
Toxic and corrosive fumes.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure effects
Prolonged exposure may cause nausea, headache, dizziness and eye damage.
   Ingestion
Nausea, vomiting and diarrhea are possible if ingested.
   Inhalation
Cough, tachypnea, and wheezing are common after inhalation.
   Skin
Redness, swelling and pain may occur.
   Eyes
Irritation.

First aid
 
   Ingestion
Emesis is not indicated due to the irritant nature of these agents. Charcoal - not recommended; it may promote vomiting and make endoscopic evaluation difficult. Immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 4 ounces/120 ml in a child). Neutralization - neutralization is not indicated. Although these agents are irritants, and therefore should not produce tissue damage, it is almost impossible to assure that a particular substance under a particular set of circumstances would not cause damage. Therefore, each patient should be examined with the idea that mucous membrane damage might have occurred.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. If in a medical facility, sterile saline should be used to irrigate the eyes until the cul de sac is returned to neutrality. Some alkali exposures may require prolonged irrigation.

Transport.