2-Chloroacetamide

  • alpha-Chloroacetamide
Formula
ClCH2CONH2
Structure
Description
Yellow to colorless crystals with a characteristic odor.

Registry Numbers and Inventories.
CAS
79-07-2
EC (EINECS/ELINCS)
201-174-2
EC Index Number
616-036-00-0
EC Class
Toxic for reproduction Category 3; Toxic; Sensitising
R 25 43 62
S 22 36/37 45
RTECS
AB5075000
RTECS class
Mutagen
UN (DOT)
2811
Merck
13,2127
Beilstein/Gmelin
878191
Beilstein Reference
4-02-00-00490
Swiss Giftliste 1
G-1379
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H4ClNO
Formula mass
93.51
Melting point, °C
115 - 117
Boiling point, °C
256
Vapor pressure, mmHg
0.016 (25 C)
Vapor density (air=1)
3.2
Density
1.60 g/cm3 (20 C)
Solubility in water
980 g/L (20 C)
Partition coefficient, pKow
-0.85
Heat of vaporization
49.4 kJ/mol
Heat of combustion
-1016 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Do not get on skin or in eyes. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents
Decomposition
Chlorine, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
109
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Reproductive effects have been reported in animals.
   Ingestion
May cause liver damage. May cause damage to pancreas. May cause heart damage. May cause paralysis of the extremities. Causes digestive tract irritation with possible burns.
   Inhalation
May cause allergic respiratory reaction. May cause dyspnea (difficult breathing from shortness of breath). May cause headache. May cause nausea and possible vomiting. Causes severe respiratory tract irritation with possible burns.
   Skin
Causes skin burns. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
Causes eye burns.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
HS Code
2924 19 00