2-Chloroacetophenone

  • Phenacyl chloride
  • 2-Chloro-1-phenylethanone
  • alpha-Chloroacetophenone
Formula
C6H5COCH2Cl
Structure
Description
A white crystalline solid. Has a floral odor.
Uses
Riot control agent.

Registry Numbers and Inventories.
CAS
532-27-4
EC (EINECS/ELINCS)
208-531-1
R 23/25 36/37/38
S 22 26 36/37/39 45
RTECS
AM6300000
RTECS class
Tumorigen; Mutagen; Human Data; Primary Irritant
UN (DOT)
1697
Merck
13,2132
Beilstein/Gmelin
507950
Beilstein Reference
4-07-00-00641
EPA OPP
18001
Swiss Giftliste 1
G-1381
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C8H7ClO
Formula mass
154.6
Melting point, °C
56.5
Boiling point, °C
244
Vapor pressure, mmHg
0.03 (25 C)
Vapor density (air=1)
5.2
Odor Threshold Odor threshold 0.1 mg/m3
Density
1.324 g/cm3 (15 C)
Solubility in water
Insoluble
Refractive index
1.5438
Partition coefficient, pKow
2.11
Heat of vaporization
48.2 kJ/mol
Heat of combustion
-3321 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Do not store in metal containers. Keep containers tightly closed. Store protected from moisture.
Handling
Wash hands before eating. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear a chemical apron. Wear butyl rubber gloves, apron, and/or clothing. Clothing: Wear a chemical apron. Wear butyl rubber gloves, apron, and/or clothing.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation. Do not get water inside containers.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Bases - amines - alcohols - moist air or water.
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
88
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Contact with metals may evolve flammable hydrogen gas. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Irritating hydrogen chloride may form.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 0.05 ppm; 0.32 mg/m3 (ACGIH 1993-1994). OSHA PEL: TWA 0.3 mg/m3 (0.05 ppm) NIOSH REL: TWA 0.3 mg/m3 (0.05 ppm) NIOSH IDLH: 15 mg/m3
Poison_Class
1
Exposure effects
Agitation and syncope, both attributed to panic, have been reported.
   Ingestion
May be fatal if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
May cause respiratory tract irritation. Inhalation may produce coughing, nausea, and pulmonary edema. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions.
   Skin
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Causes redness and pain. Causes skin irritation and possible burns.
   Eyes
Lachrymator. Causes eye irritation and possible burns. May cause reversible inflammation and corneal injury with opacity.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Get medical aid if irritation or symptoms occur.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
If irritation develops, get medical aid. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
1697
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
CRA
 
Std. Transport #
4923409