2-Chloroaniline

  • o-Chloroaniline
  • 2-Chloroaminobenzene
  • 1-Amino-2-chlorobenzene
  • Fast yellow GC base
Formula
2-(Cl)C6H4NH2
Structure
Description
Clear colorless to amber liquid, darkens on exposure to air, characteristic sweet amine odor.
Uses
Dye, pesticide, pigment, rubber chemicals intermediate.

Registry Numbers and Inventories.
CAS
95-51-2
EC (EINECS/ELINCS)
202-426-4
EC Index Number
612-010-00-8
EC Class
toxic, dangerous for the environment
R 23/24/25 33 50/53
S 28 36/37/39 45 60 61
RTECS
BX0525000
RTECS class
Tumorigen; Mutagen
UN (DOT)
2019
Merck
13,2136
Beilstein/Gmelin
606077
Beilstein Reference
4-12-00-01115
Swiss Giftliste 1
G-4899
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H6ClN
Formula mass
127.57
Melting point, °C
-3
Boiling point, °C
208
Vapor pressure, mmHg
19.5 (100 C)
Vapor density (air=1)
4.41
Saturation Concentration
20 ppm (0.0020%) at 20 C (calculated)
Critical temperature
460
Critical pressure
46.4
Density
1.213 g/cm3 (20 C)
Solubility in water
Insoluble
Viscosity
2.9157 cp @ 20C
Surface tension
43.66 g/s2 at 20 C
Refractive index
1.5895 (20C)
pKa/pKb
11.34 (pKb)
Partition coefficient, pKow
1.90
Heat of fusion
11.9 kJ/mol
Heat of vaporization
57.5 kJ/mol
Heat of combustion
-774 kJ/mol

Hazards and Protection.
Storage
Poison room locked.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with skin and eyes. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, acid chlorides, acid anhydrides, strong oxidizing agents.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
105
Autoignition, °C
> 500
Upper exp. limit, %
8.8
Lower exp. limit, %
1.5
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
This chemical is combustible.
Hazards
Containers may explode when heated.
Combustion products
Irritating and toxic hydrogen chloride and oxides of nitrogen may form in fires.

Health.
Exposure limit(s)
NIOSH: Potential Occupational Carcinogen.
Poison_Class
3
Exposure effects
May cause cancer according to animal studies.
   Ingestion
May cause irritation of the digestive tract. May cause methemoglobinemia, cyanosis, convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May cause skin eruptions and/or acne.
   Inhalation
May cause respiratory tract irritation. May cause effects similar to those described for ingestion.
   Skin
Causes skin irritation. May be absorbed through the skin in harmful amounts. Produces acneiform eruptions.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if symptoms occur.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2019
Response guide
Hazard class
6.1
Packing Group
II
 
HS Code
2921 42 10