2-Chlorophenyl isothiocyanate

  • o-Chlorophenyl isothiocyanate
  • 1-Chloro-2-isothiocyanatobenzene
  • Isothiocyanic acid, o-chlorophenyl ester
Formula
C7H4ClNS
Structure
Description
Clear faint yellow liquid.

Registry Numbers and Inventories.
CAS
2740-81-0
R 23/24/25 36/37/38
S 26 36/37/39 45
UN (DOT)
2811
Beilstein/Gmelin
2081473
Beilstein Reference
4-12-00-01129

Properties.
Formula
C7H4ClNS
Formula mass
169.62
Boiling point, °C
260
Vapor density (air=1)
5.85
Density
1.29 g/cm3
Solubility in water
Insoluble
Refractive index
1.66 (20 C)

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Do not allow contact with water. Keep from contact with moist air and steam. Do not breathe vapors.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Provide ventilation. Do not get water inside containers.
Stability
Stable under normal temperatures and pressures. May decompose on exposure to moist air or water.
Incompatibilities
Moisture, water, alcohols, amines, acids, heat, strong oxidizing agents, strong bases.
Decomposition
Hydrogen chloride, hydrogen cyanide, nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
> 110
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
0
 
 
Reactivity
1
 

Health.
Exposure effects
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May cause burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation. Lachrymator.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III