2-Chloropropionic acid

  • alpha-Chloropropionic Acid
Formula
CH3CHClCOOH
Structure
Description
A pale liquid with a slight odor.
Uses
Intermediate for weed killers.

Registry Numbers and Inventories.
CAS
598-78-7
EC (EINECS/ELINCS)
209-952-3
EC Index Number
607-139-00-1
EC Class
Harmful; Corrosive
R 22 35
S 23 26 28 36 45
RTECS
UE8575000
RTECS class
Other
UN (DOT)
2511
Beilstein/Gmelin
1720259
Beilstein Reference
0-02-00-00248
Swiss Giftliste 1
G-6809
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H5ClO2
Formula mass
108.53
Melting point, °C
-12
Boiling point, °C
180
Vapor pressure, mmHg
0.26 (25 C)
Vapor density (air=1)
3.7
Critical temperature
399
Density
1.28 g/cm3 (0 C)
Solubility in water
Soluble
Refractive index
1.4360 (20 C)
pKa/pKb
2.96 (pKa)
Partition coefficient, pKow
0.30
Heat of vaporization
46.9 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use. Corrosives area.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not ingest or inhale. Discard contaminated shoes.
Protection
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Disposal code
4
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Reacts with aqueous solutions containing a chemical base and dissolves if neutralization generates a soluble salt May react with active metals to form gaseous hydrogen and a metal salt Reacts with cyanide salts to generate gaseous hydrogen cyanide Reacts with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides to generate flammable and/or toxic gases and heat Reacts with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat Reacts with carbonates and bicarbonates to generate a harmless gas (carbon dioxide) but some heat.
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
102
Autoignition, °C
550
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
May contain hydrogen chloride and phosgene.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OEL-RUSSIA:STEL 2 mg/m3Skin
Poison_Class
4
Exposure effects
Effects may be delayed.
   Ingestion
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May be harmful if swallowed. May cause systemic effects.
   Inhalation
Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. May cause systemic effects.
   Skin
Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Causes eye burns. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2511
Response guide
Hazard class
8
Packing Group
III
 
USCG CHRIS Code
CLA
 
HS Code
2915 90 80
 
IMO Chemical Code
17
IMO Pollution Category
C
IMO Hazard code
S/P