2-Ethylaniline

  • 2-Ethylbenzenamine
  • o-Amino ethylbenzene
Formula
2-(C2H5)C6H4NH2
Structure
Description
A brown liquid.
Uses
Intermediate for pharmaceuticals, dyestuffs, pesticides, and other products.

Registry Numbers and Inventories.
CAS
578-54-1
EC (EINECS/ELINCS)
209-424-2
EC Class
harmful
R 20/21/22 33
S 28 36/37
RTECS
BX9800000
RTECS class
Other
UN (DOT)
2273
Beilstein/Gmelin
1841268
Beilstein Reference
4-12-00-02411
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C8H11N
Formula mass
121.18
Melting point, °C
-46
Boiling point, °C
210
Vapor pressure, mmHg
0.2
Vapor density (air=1)
4.17
Critical temperature
431
Critical pressure
36.9
Density
0.983 g/cm3 (20 C)
Solubility in water
Insoluble
Viscosity
9.10 cp (98.9 C)
Surface tension
4.8559x10-2 n/m @ -46.5 C
Refractive index
1.5609 (20 C)
pKa/pKb
9.70 (pKb)
Partition coefficient, pKow
1.74
Heat of vaporization
60.32 kJ/mol
Heat of combustion
-4695 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Remove all sources of ignition. Provide ventilation. Cover with dry earth, dry sand, or other non-combustible material followed with plastic sheet to minimize spreading and contact with water. Stop leak only if you can do so without risk.
Disposal code
5
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
92
Upper exp. limit, %
6.7
Lower exp. limit, %
1
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. This material is lighter than water and insoluble in water. The fire could easily be spread by the use of water in an area where the water cannot be contained. Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Fire potential
May burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure limit(s)
2 ppm TWA ACGIH
Exposure effects
Acute poisoning may cause rapid heart rate and rapid breathing. Severe headache, CNS disturbances, and tremor may occur. A high incidence of gynecological disorders and excess frequency of spontaneous abortions have been noted. The fetal liver can n-oxygenate aniline to form phenylhydroxylamine. Fetal effects include higher levels of methemoglobin those found in than the mother. Fetal poisoning may occur. <br>No data were available to assess the potential effects of exposure to aniline during lactation. <br>No information about possible male reproductive effects was found in available references at the time of this review
   Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation. May be absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2273
Response guide
Hazard class
6.1
Packing Group
III
 
9. Aromatic amines
HS Code
2921 49 80
 
Std. Transport #
4925114