- o-Fluorobenzoyl chloride
Chemical intermediate for flunitrazepam, a hypnotic drug.
Registry Numbers and Inventories.
S 26 36/37/39 45
Melting point, °C
4 - 6
Boiling point, °C
Vapor pressure, mmHg
0.3 (25 C)
Solubility in water
1.5365 (20 C)
Partition coefficient, pKow
Heat of vaporization
Hazards and Protection.
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.
Stable under normal temperatures and pressures.
Alcohols, strong bases, oxidizing agents.
Hydrogen chloride, phosgene, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Containers may explode when heated. Extinguishing media: Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. Use agent most appropriate to extinguish fire.
This chemical is combustible.
Contact with metals may evolve flammable hydrogen gas.
Fire may produce irritating, corrosive and/or toxic gases.
Hyperactive reflexes, painful muscle spasms, weakness and tetanic contractures may be noted due to fluoride induced hypocalcemia. Prenatal fluoride supplementation (2.2 mg NaF or 1 mg fluoride daily) during the last two trimesters of pregnancy has been reported to be safe.
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
May cause skin irritation and possible burns. The toxicological properties of this material have not been fully investigated.
May cause eye irritation and possible burns. Lachrymator. The toxicological properties of this material have not been fully investigated.
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
I; II; III
2916 39 00