2-Hexanone

  • Methyl n-butyl ketone
  • Propylacetone
  • n-Butyl methyl ketone
  • Hexan-2-one
Formula
CH3COC4H9
Structure
Description
A clear colorless liquid.
Uses
Solvent for lacquers, ink thinners, nitrocellulose, resins, oils, fats and waxes.

Registry Numbers and Inventories.
CAS
591-78-6
EC (EINECS/ELINCS)
209-731-1
EC Index Number
606-030-00-6
EC Class
Flammable; Toxic for reproduction Category 3; Toxic; Vapours may cause drowsiness and dizziness
R 10 48/23 62 67
S 36/37 45
RTECS
MP1400000
RTECS class
Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
1224
Merck
12,6112
Beilstein/Gmelin
1737676
Beilstein Reference
4-01-00-03298
Swiss Giftliste 1
G-2440
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H12O
Formula mass
100.16
Melting point, °C
-56.9
Boiling point, °C
127
Vapor pressure, mmHg
12
Vapor density (air=1)
3.45
Evaporization number
1.2 (butyl acetate=1)
Odor Threshold Odor threshold 3 ppm
Critical temperature
314
Critical pressure
32.44
Density
0.812 g/cm3 (20 C)
Solubility in water
14 g/L
Viscosity
0.58 cp (25 C)
Surface tension
25.49 g/s2
Refractive index
1.40061 (15 C)
Partition coefficient, pKow
1.38
Heat of fusion
7.5 kJ/mol
Heat of vaporization
43.03 kJ/mol
Heat of combustion
-3686 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Flammables-area.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents, reducing agents, strong bases.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
25
Autoignition, °C
424
Upper exp. limit, %
8
Lower exp. limit, %
1.2
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water.
Fire potential
This chemical is flammable.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 5 ppm; 20 mg/m3 (skin) (ACGIH 1991-1992). OSHA PEL: TWA 100 ppm (410 mg/m3) NIOSH REL: TWA 1 ppm (4 mg/m3) NIOSH IDLH: 1600 ppm
Poison_Class
4
Exposure effects
Prolonged or repeated skin contact may cause dermatitis. Chronic exposure produces peripheral neuropathy.
   Ingestion
May cause irritation of the digestive tract. May cause central nervous system depression.
   Inhalation
Causes respiratory tract irritation. May cause narcotic effects in high concentration. May cause drowsiness, unconsciousness, and central nervous system depression.
   Skin
Causes mild skin irritation. May be absorbed through the skin in harmful amounts. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
   Eyes
Causes mild eye irritation. Causes minor transient corneal injury.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1224
Response guide
Hazard class
3
Packing Group
I; II; III
 
USCG CHRIS Code
MBK
 
Std. Transport #
4909242
 
IMO Chemical Code
18
IMO Pollution Category
D