2-Hydroxybenzeneacetic acid

  • (o-Hydroxyphenyl)acetic acid
  • (2-Hydroxyphenyl)acetic acid
  • 2-HPAA
Formula
C8H8O3
Structure
Description
Beige powder.

Registry Numbers and Inventories.
CAS
614-75-5
EC (EINECS/ELINCS)
210-393-2
EC Class
irritant
R 36/37/38
Beilstein/Gmelin
908000
Beilstein Reference
4-10-00-00536
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed

Properties.
Formula
C8H8O3
Formula mass
152.15
Melting point, °C
145 - 146
Boiling point, °C
328
Vapor pressure, mmHg
8E-5 (25 C)
Solubility in water
Very soluble
pKa/pKb
4.17 (pKa)
Partition coefficient, pKow
0.77
Heat of vaporization
60.2 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Bases, acid chlorides, acid anhydrides, oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
167
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth respiration if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2918 29 90