2-Methyl-1-nitroanthraquinone

  • 2-Methyl-1-nitro-9,10-anthracenedione
  • 1-Nitro-2-methylanthraquinone
  • Violet cibacet 2r
Formula
C15H9NO4
Structure
Description
Pale yellow needles or light yellow solid.
Uses
Dye intermediate, manufacture 1-amino-2-methylanthraquinone.

Registry Numbers and Inventories.
CAS
129-15-7
EC (EINECS/ELINCS)
204-932-0
RTECS
CB7920000
RTECS class
Tumorigen; Mutagen
Beilstein/Gmelin
2140943
Beilstein Reference
4-07-00-02576
Japan ENCS (MITI)
Listed

Properties.
Formula
C15H9NO4
Formula mass
267.24
Melting point, °C
270-271
Solubility in water
insoluble
Partition coefficient, pKow
1.87

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Dispensers of liquid detergent should be available. In the laboratory, gloves and protective clothing should always be worn but should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, and disposable plastic aprons might provide additional protection. Protective clothing should be of distinctive color, as a reminder not to be worn outside the laboratory.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Small spills/leaks
If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This material is probably combustible.

Health.
Carcinogin
I-2B, CP65
Exposure effects
Muscular seizures are a rare sign of severe intoxication. Dizziness is occasionally seen in severe intoxications. CNS depression was seen in animals tested with injections of emodin. Analgesia was also noted with injection. These effects have not been noted in human overdose.
   Ingestion
Nausea, vomiting, abdominal pain, and especially diarrhea may be seen with both therapeutic doses and overdose.
   Inhalation
Dyspnea is mentioned as a sign of severe poisoning.
   Skin
Some anthraquinones have been shown to be sensitizers. Finger clubbing has been reported with abuse of senna. The condition is reversible with discontinuation of the drug. Dithranol may cause a burning sensation, especially on perilesional skin.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.