2-Methyl-1,4-benzenediamine

  • 4-Amino-2-methylaniline
  • 2,5-Diaminotoluene
  • 2-Methyl-para-phenylenediamine
  • para-Toluenediamine
  • Toluene-2,5-diamine
  • p-Toluylendiamine
Formula
C7H10N2
Structure
Description
Plates from benzene.
Uses
Intermediate in prodn of two dyes, ci basic red 2 & ci acid brown 103, in hair dyes.

Registry Numbers and Inventories.
CAS
95-70-5
EC (EINECS/ELINCS)
202-442-1
EC Index Number
612-125-00-3
EC Class
Toxic; Harmful; Sensitising; Dangerous for the Environment
RTECS
XS9700000
RTECS class
Tumorigen; Mutagen; Primary Irritant
UN (DOT)
3259
Beilstein/Gmelin
774521
Beilstein Reference
4-13-00-00246
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H10N2
Formula mass
122.19
Melting point, °C
150 - 155
Boiling point, °C
273
Vapor pressure, mmHg
0.006 (25 C)
Solubility in water
Soluble
pKa/pKb
7.83 (pKb)
Partition coefficient, pKow
0.25
Heat of vaporization
51.2 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
No data.

Fire.
Flash Point,°C
140
Fire fighting
DOT recommendations-for small fires, use dry chemicals, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam. If you can do it without risk, move containers from fire area.
Fire potential
Burns but does not ignite readily.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Abnormally low blood pressure and labored respirations may occur. CNS depression and peripheral neuropathy have been reported after ingestion.
   Ingestion
Epigastric pain and recurrent vomiting are common shortly following ingestion.
   Inhalation
Bronchospasm may develop in sensitized individuals.
   Skin
Contact dermatitis is common.
   Eyes
Significant laryngeal and facial edema may occur. Breathing may be impaired as a result of laryngeal edema. Immediate (usually) or delayed hypersensitivity reactions have been described following application of PPD-containing hair dyes to eyebrows or eyelashes. Eye pain and burning, and edema occur, which may progress to widespread facial edema, dermatitis, tearing, photophobia, uveitis, and keratitis. Corneal necrosis and vision loss may occur. Bilateral optic neuritis has been reported with blindness.

First aid
 
   Ingestion
Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
3259
Response guide
Hazard class
8
Packing Group
I; II; III
 
9. Aromatic amines