2-Methyl-2-propenoyl chloride

  • Methacrylic acid chloride
Formula
C4H5ClO
Structure
Description
Colorless to yellow liquid.
Uses
A hydrogel with 80% water absorption was obtained from reaction of 2-hydroxyethyl methacrylate, containing small amounts of ethylene glycol dimethacrylate with the reaction product of poly(vinylpyrrolidinone) & methacryloyl chloride contact lenses.

Registry Numbers and Inventories.
CAS
920-46-7
EC (EINECS/ELINCS)
213-058-9
R 11 22 26 34 37
S 16 26 28 36/37/39 45
RTECS
OZ5791000
RTECS class
Other
UN (DOT)
3286
Beilstein/Gmelin
878175
Beilstein Reference
4-02-00-01537
Canada DSL/NDSL
DSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C4H5ClO
Formula mass
104.54
Melting point, °C
-60
Boiling point, °C
95
Vapor pressure, mmHg
44 (25 C)
Density
1.0562 g/cm3 (20 C)
Solubility in water
Slightly soluble
Refractive index
1.4433
Partition coefficient, pKow
1.61
Heat of vaporization
33.6 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Refrigerator/flammables.
Handling
Wash thoroughly after handling. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Avoid contact with heat, sparks and flame. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide, chloride fumes.

Fire.
Flash Point,°C
4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure effects
   Ingestion
Irritation or burns of the esophagus or gastrointestinal tract may follow ingestion.
   Inhalation
May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
   Skin
Dermal irritation and burning may occur. Sensitization is predicted.
   Eyes
Causes severe eye burns. Lachrymator.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
3286
Response guide
USCG CHRIS Code
MLC