2-Nitro-1-phenylethanone

  • 2-Nitroacetophenone
  • a-Nitroacetophenone
  • Benzoylnitromethane
  • Nitromethyl phenyl ketone
  • NSC 4509
Formula
C8H7NO3
Structure

Registry Numbers and Inventories.
CAS
614-21-1
20/21/22 36/37/38
26 37/39
Beilstein Reference
4-07-00-00659

Properties.
Formula
C8H7NO3
Formula mass
165.15
Melting point, °C
106
Boiling point, °C
299
Vapor pressure, mmHg
0.0013 (25 C)
Density
1.234 g/cm3 (20 C)
Solubility in water
1.6 g/L (25 C)
Refractive index
1.5468 (30<sup>o</sup>C)
pKa/pKb
5.36 (pKa)
Partition coefficient, pKow
1.68
Heat of vaporization
53.85 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place. Store at 2 - 8 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Incompatibilities
Moisture, Strong oxidizing agents, Strong bases.
Decomposition
Oxides of carbon and nitrogen.

Fire.
Flash Point,°C
147
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Material is irritating to mucous membranes and upper respiratory tract. Causes eye and skin irritation. May be harmful by inhalation, ingestion, or skin absorption.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.