2-Nitro-4-isocyanatotoluene

  • 4-Isocyanato-2-nitrotoluene
  • 4-Nitro-4-methylphenyl isocyanate
  • 4-Methyl-3-nitrophenyl isocyanate
  • Isocyanic acid, 3-nitro-p-tolyl ester
  • Benzene, 4-isocyanato-1-methyl-2-nitro-
Formula
C8H6N2O3
Structure
Description
Yellow solid.

Registry Numbers and Inventories.
CAS
13471-69-7
R 20/21/22 36/37/38 42
S 22 26 36/37/39 45
UN (DOT)
2811
Beilstein/Gmelin
2724128
Beilstein Reference
3-12-00-02173
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C8H6N2O3
Formula mass
178.14
Melting point, °C
49 - 50
Boiling point, °C
100 - 102 (0.2 torr)
Solubility in water
Insoluble

Hazards and Protection.
Storage
Store in a tightly closed container. Keep under a nitrogen blanket. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Do not expose to air. Store protected from moisture. Store under an inert atmosphere.
Handling
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Handle under an inert atmosphere. Store protected from air. Do not allow contact with water. Wash clothing before reuse. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Place under an inert atmosphere. Do not get water inside containers.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
> 110
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. May cause nausea and vomiting.
   Inhalation
Causes respiratory tract irritation. May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. The toxicological properties of this substance have not been fully investigated.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation. Lachrymator.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2811
Response guide