2-Nitropropane

  • Isonitropropane
  • Dimethylnitromethane
  • sec-Nitropropane
Formula
(CH3)2CHNO2
Structure
Description
Clear, colorless, oily liquid with a pleasant, mild odor described as fruity.
Uses
Chemical synthesis, rocket propellant, gasoline additive.

Registry Numbers and Inventories.
CAS
79-46-9
EC (EINECS/ELINCS)
201-209-1
EC Index Number
609-002-00-1
EC Class
Flammable; Carcinogenic Category 2; Harmful
R 45 10 20/22
RTECS
TZ5250000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data
UN (DOT)
2608
Merck
12,6725
Beilstein/Gmelin
1740684
Beilstein Reference
4-01-00-00230
RCRA
U171
EPA OPP
600029
Swiss Giftliste 1
G-2652
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H7NO2
Formula mass
89.09
Melting point, °C
-91
Boiling point, °C
120.3
Vapor pressure, mmHg
13 (20 C)
Vapor density (air=1)
3.06
Saturation Concentration
1.7 percent (20 C)
Evaporization number
1.1 (n-butyl acetate = 1)
Odor Threshold Odor threshold 25 ppm
Density
0.9927 g/cm3 (20 C)
Solubility in water
20 g/L
Viscosity
0.770 cp (20 C)
Surface tension
29.08 g/s2 (21 C)
Refractive index
1.3944 (20 C)
Dipole moment
3.73 D (20 C)
Dielectric constant
25.2 (20 C)
pKa/pKb
8.44 (pKa)
Partition coefficient, pKow
0.68
Heat of vaporization
41.0 kJ/mol
Heat of combustion
-1996 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store near combustible materials. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
B2 D1A D2A D2B
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. A vapor suppressing foam may be used to reduce vapors.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong acids, strong bases, copper, copper alloys, chlorosulfonic acid, oleum, lead, amines + heavy metal oxides (e.g. mercury oxide or silver oxide), carbon + hopcalite (catalyst consisting of coprecipitated copper (II) oxide and manganese (IV) oxide), stong alkalies.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
26
Autoignition, °C
425
Upper exp. limit, %
11
Lower exp. limit, %
2.6
Fire fighting
Wear a self-contained breathing apparatus with a full facepiece operated in the positive pressure demand mode with appropriate turn-out gear and chemical resistant personal protective equipment, Extinguishing media include regular foam, carbon dioxide, dry chemical
Fire potential
Moderately flammable. Combustion with moderate heating.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Toxic oxides of nitrogen may form in fire.
Health
1
 
Flammability
3
 
 
Reactivity
1
 

Health.
Exposure limit(s)
TLV: 10 ppm; 36 mg/m3 A2 (as TWA) (ACGIH 994-1995). OSHA PEL: TWA 25 ppm (90 mg/m3) NIOSH REL: Ca See Appendix A NIOSH IDLH: Potential occupational carcinogen 100 ppm
Carcinogin
G-A3, I-2B, N-2, CP65
Poison_Class
1*
Exposure effects
Signs and symptoms of exposure to this material through breathing, swallowing, and/or passage of the material through the skin may include: stomach or intestinal upset (nausea, vomiting, diarrhea irritation (nose, throat, airways), central nervous system depression (dizziness, drowsiness, weakness, fatigue, nausea, headache, unconsciousness), and death. Overexposure to this material (or its components) has been suggested as a cause of the following effects in laboratory animals: blood abnormalities, liver abnormalities, kidney damage, lung damage, brain damage.
   Ingestion
Swallowing small amounts of this material during normal handling is not likely to cause harmful effects. Swallowing large amounts may be harmful.
   Inhalation
Breathing of vapor or mist is possible. Breathing small amounts of this material during normal handling is not likely to cause harmful effects. Breathing large amounts may be harmful 2-Nitropropane has been linked with several work-related deaths from irreversible liver damage caused when 2-nitropropane-containing products were applied in confined or enclosed spaces without use of adequate respiratory protection or adequate ventilation.
   Skin
May cause mild skin irritation. Symptoms may include redness and burning of skin.
   Eyes
May cause mild eye irritation. Symptoms include stinging tearing, and redness.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2608
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
NPP
 
42 Nitrocompounds
HS Code
2904 20 00
 
IMO Chemical Code
17
IMO Pollution Category
D
IMO Hazard code
S