2-Phenoxyethanol

  • Phenyl cellosolve
  • Ethylene glycol monophenyl ether
  • Arosol
Formula
C6H5OCH2CH2OH
Structure
Description
Colorless liquid with a pleasant odor.
Uses
Fixative for perfumes, in organic synthesis, as bactericide in conjuction with quaternary ammonium compound, as insect repellent.

Registry Numbers and Inventories.
CAS
122-99-6
EC (EINECS/ELINCS)
204-589-7
EC Index Number
603-098-00-9
EC Class
Harmful; Irritant
R 22 36
RTECS
KM0350000
RTECS class
Mutagen; Primary Irritant
Merck
12,7410
Beilstein/Gmelin
1364011
Beilstein Reference
4-06-00-00571
Swiss Giftliste 1
G-1809
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H10O2
Formula mass
138.17
Melting point, °C
13
Boiling point, °C
245
Vapor pressure, mmHg
0.03 (20 C)
Vapor density (air=1)
4.77
Density
1.1094 g/cm3
Solubility in water
27 g/L
Viscosity
30.50 cp (20 C)
Surface tension
42.99 g/s2 (30 C)
Refractive index
1.5341 (17 C)
Partition coefficient, pKow
1.16
Heat of vaporization
39.74 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Wash hands before eating. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents - acid chlorides - acid anhydrides.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
121
Autoignition, °C
535
Upper exp. limit, %
9.0
Lower exp. limit, %
1.4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
This chemical is combustible.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Chronic ingestion may cause effects similar to those of acute ingestion.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause kidney failure. May be harmful if swallowed. Lesions may appear in the brain, lungs, liver, meninges, and heart.
   Inhalation
May cause respiratory tract irritation.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.

Transport.
USCG CHRIS Code
EPE
 
40 Glycol ethers
HS Code
2909 49 90
 
IMO Chemical Code
18
IMO Pollution Category
D