2-Phenylethylamine

  • beta-aminoethylbenzene
  • (2-aminoethyl)benzene
  • 1-Amino-2-phenylethane
  • 2-Amino-1-phenylethane
  • Benzeneethanamine
  • Phenethylamine
Formula
C6H5CH2CH2NH2
Structure
Description
Liquid. Fishy odor.
Uses
Organic synthesis, laboratory reagent, scintillation counter (co2 absorber).

Registry Numbers and Inventories.
CAS
64-04-0
EC (EINECS/ELINCS)
200-574-4
EC Class
harmful, corrosive, dangerous for the environment
R 22 35
S 26 36/37/39 45
RTECS
SG8750000
RTECS class
Other
UN (DOT)
2733
Merck
12,7371
Beilstein/Gmelin
507488
Beilstein Reference
4-12-00-02453
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H11N
Formula mass
121.18
Melting point, °C
-60
Boiling point, °C
200
Vapor pressure, mmHg
0.312 (25 C)
Vapor density (air=1)
4.18
Density
0.9639 g/cm3 (20 C)
Solubility in water
soluble
Refractive index
1.5332
pKa/pKb
4.10 (pKb)
Partition coefficient, pKow
-1.39
Heat of vaporization
43.3 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Keep under an argon blanket. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store under an inert atmosphere.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Handle under an inert atmosphere. Store protected from air. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Place under an inert atmosphere. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Disposal code
5
Stability
Stable under normal temperatures and pressures. Absorbs carbon dioxide from the air.
Incompatibilities
Strong oxidizing agents, acids, carbon dioxide, acid anhydrides, acid chlorides, air.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
81
Autoignition, °C
425
Upper exp. limit, %
5.5
Lower exp. limit, %
1.0
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Containers may explode when heated. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
Flammable/combustible material. May be ignited by heat, sparks or flames.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed. Symptoms of exposure may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting.
   Ingestion
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause central nervous system effects. May be harmful if swallowed. May cause systemic effects.
   Inhalation
Causes chemical burns to the respiratory tract. May cause severe irritation of the respiratory tract with possible burns. Aspiration may lead to pulmonary edema. May cause systemic effects. Inhalation at high concentrations may cause CNS depression and asphixiation.
   Skin
Causes skin burns. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause irritation and dermatitis. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Causes eye burns. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2733
Response guide
Hazard class
3
Packing Group
I; II; III
 
9. Aromatic amines
HS Code
2921 49 80