- Freon 123
Clear, colorless liquid with a slight ethereal odor.
Refrigerant to replace cfc-11 in commercial chillers and air conditioning units.
Registry Numbers and Inventories.
Tumorigen; Drug; Mutagen; Reproductive Effector; Primary Irritant
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
633 (25 C)
1.4885 g/cm3 (10 C)
Solubility in water
0.0111 cp (35 C)
6.97 g/s2 (100 C)
1.3392 (10 C)
Partition coefficient, pKow
Heat of vaporization
Hazards and Protection.
Stor cylinders in a dry, well vented area, way from heat and traffic..
Protect cylinders aganst damage. ground sylinders. Do not use near incompatible materials.
Many of the fluorocarbons are good solvents of skin oil, so protective ointment should be used. Neoprene gloves, protective clothing, and eye protection minimize risk of topical contact. Degreasing effect on skin can be treated with lanolin ointment. Forced air ventilation @ level of vapor concentration together with use of individual breathing devices with independent air supply will minimize risk of inhalation. Lifelines should be worn when entering tanks or other confined spaces.
Self contained breathing apparatus.
Proper protective equipment should be used. Stop leak if you can do so without risk. Allow to evaporate. Rinse area with soap and watter.
Stable at normal temperatures and pressures.
Strong oxidizing agents.
Hydrogen fluoride, phosgene, hydrogen chloride and carbonyl fluoride.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
All fluorocarbons will undergo thermal decomposition when exposed to flame or red-hot metal.
Headache, dizziness, and disorientation are common. Cerebral edema may be found on autopsy. Dichlorodifluoromethane was not teratogenic in rats and rabbits. <br>The reproductive effects of 1,1,1,2-tetrafluoroethane were studied in rats. No adverse effects on reproductive performance was noted or on the development, maturation or reproductive performance of up to two successive generations.
Nausea may develop. Ingestion of a small amount of trichlorofluoromethane resulted in necrosis and perforation of the stomach in one patient.
Pulmonary irritation, bronchial constriction, cough, dyspnea, and chest tightness may develop after inhalation. Chronic pulmonary hyperreactivity may occur. Adult respiratory distress syndrome has been reported following acute inhalational exposures. Pulmonary edema is an autopsy finding in fatal cases.
Dermal contact may result in defatting, irritation or contact dermatitis. Severe frostbite has been reported as an effect of freon exposure. Injection causes transient pain, erythema and edema.
These substances may cause frostbite to the upper airway and gastrointestinal tract after ingestion. Administer oxygen and manage airway as clinically indicated. Emesis, activated charcoal, and gastric lavage are not recommended.
Provide a quiet calm atmosphere to prevent adrenaline surge if the patient is seen before the onset of cardiac arrhythmias. Minimize physical exertion.
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. If frostbite has occurred, refer to dermal treatment in the main body of this document for rewarming.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Ophthamologic consultation should be obtained in any symptomatic patients.
36. Halogenated hydrocarbons