2,2'-Dichlorodiethylamine hydrochloride

  • Bis(2-chloroethyl)amine hydrochloride
  • 2-Chloro-N-(2-chloroethyl)ethanamine hydrochloride
  • Bis(2-chloroethyl)ammonium chloride
  • N,N-Bis(2-chloroethyl)amine hydrochloride
  • Nornitrogen mustard hydrochloride
  • NSC 10873
Formula
(ClCH2CH2)2NH2Cl
Structure
Description
White to light beige powder.

Registry Numbers and Inventories.
CAS
821-48-7
EC (EINECS/ELINCS)
212-479-5
EC Class
harmful, irritant
R 21/22 23 34 68
S 22 26 36/37/39 45
RTECS
IA1225000
RTECS class
Mutagen; Reproductive Effector
UN (DOT)
3261
Beilstein/Gmelin
3550356
Beilstein Reference
3-04-00-00238
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C4H10Cl3N
Formula mass
178.49
Melting point, °C
212 - 215
Density
1.412 g/cm3
Solubility in water
< 100 g/L (20 C)

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use with adequate ventilation. Wash clothing before reuse. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents, strong bases.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause severe and permanent damage to the digestive tract. May cause systemic effects. May cause central nervous system effects including confusion, hyperreflexia, tremors, dysarthria, and seizures
   Inhalation
May cause systemic effects. Can produce delayed pulmonary edema. Causes severe respiratory tract irritation with possible burns.
   Skin
Causes skin irritation and burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Contact with eyes may cause severe irritation, and possible eye burns. Lachrymator. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
3261
Response guide
Hazard class
8
Packing Group
I; II; III
 
HS Code
2921 19 80