2,2'-Thiodiethanol

  • Thiodiglycol
  • bis(beta-Hydroxyethyl) sulfide
  • bis(2-Hydroxyethyl) sulfide
  • beta-Thiodiglycol
  • Thiodiethylene glycol
Formula
HOCH2CH2SCH2CH2OH
Structure
Description
Colorless to light yellow liquid with a stench.

Registry Numbers and Inventories.
CAS
111-48-8
EC (EINECS/ELINCS)
203-874-3
EC Index Number
603-081-00-6
EC Class
Irritant
RTECS
KM2975000
RTECS class
Primary Irritant
Merck
12,9466
Beilstein/Gmelin
1236325
Beilstein Reference
4-01-00-02437
Swiss Giftliste 1
G-4279
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H10O2S
Formula mass
122.19
Melting point, °C
-10
Boiling point, °C
282
Vapor pressure, mmHg
0.0004 (25 C)
Vapor density (air=1)
4.24
Density
1.1973 g/cm3 (0 C)
Solubility in water
Miscible
Viscosity
65.20 cp (20 C)
Surface tension
53.5 g/s2 (20 C)
Refractive index
1.5171 (21 C)
Partition coefficient, pKow
-0.60
Heat of vaporization
66.7 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Keep container tightly closed. Avoid contact with heat, sparks and flame.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
140
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
May cause kidney damage.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause irritation and dermatitis.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.