2,3-Dichlorophenyl isocyanate

  • 1,2-Dichloro-3-isocyanatobenzene
Formula
C7H3Cl2NO
Structure
Description
Light yellow liquid.

Registry Numbers and Inventories.
CAS
41195-90-8
EC (EINECS/ELINCS)
255-253-1
R 23/25 36/37/38 42
S 23 26 36/37/39 45
UN (DOT)
2250
Beilstein/Gmelin
4669222
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C7H3Cl2NO
Formula mass
188.01
Boiling point, °C
247
Vapor pressure, mmHg
0.03 (25 C)
Vapor density (air=1)
6.48
Critical temperature
477 34.7
Density
1.42 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.58 (20 C)
Partition coefficient, pKow
3.71
Heat of vaporization
48.4 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Keep under a nitrogen blanket. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from moisture.
Handling
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Do not allow contact with water. Use only in a chemical fume hood. Wash clothing before reuse. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Do not get water inside containers.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents.
Decomposition
Hydrogen chloride, hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
95
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. Cool containers with flooding quantities of water until well after fire is out. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.
Combustion products
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
Repeated exposure may cause allergic respiratory reaction (asthma).
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. May cause nausea and vomiting.
   Inhalation
Causes respiratory tract irritation. May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. The toxicological properties of this substance have not been fully investigated.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation. Lachrymator.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2250
Response guide
Hazard class
6.1
Packing Group
II