2,3,6-Trichlorophenol

  • 1-Hydroxy-2,3,6-trichlorobenzene
Formula
C6H3Cl3O
Structure
Description
Gray to dark gray crystals with a pungent, acetic acid odor.
Uses
Chlorinated phenols are used as intermediates in the synthesis of dyes, pigments, and phenolic resins. Certain chlorophenols also are used directly as flea repellents, mold inhibitors, antiseptics, disinfectants, and antigumming agents for gasoline. Chlorinated phenols.

Registry Numbers and Inventories.
CAS
933-75-5
EC (EINECS/ELINCS)
213-271-7
R 22 36/37/38
S 26 28 36/37/39
RTECS
SN1300000
RTECS class
Mutagen
UN (DOT)
2020
Beilstein/Gmelin
1867596
Beilstein Reference
4-06-00-00962
RCRA
F027
Canada DSL/NDSL
NDSL
US TSCA
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6H3Cl3O
Formula mass
197.44
Melting point, °C
58
Boiling point, °C
253
Solubility in water
Insoluble
pKa/pKb
5.8 (pKa)
Partition coefficient, pKow
3.77

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
78
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. May polymerize explosively when involved in a fire. Containers may explode when heated. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire.
Fire potential
This chemical is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Chronic inhalation may cause pulmonary fibrosis.
   Ingestion
Overexposure may cause methemoglobinemia. May cause systemic effects including renal dysfunction and impaired liver function. Causes gastrointestinal tract irritation.
   Inhalation
Causes respiratory tract irritation. May cause pulmonary fibrosis and permanent damage. May cause respiratory failure possibly leading to death. May cause seizures and blood abnormalities.
   Skin
Causes skin irritation. Causes redness and pain.
   Eyes
Causes eye irritation. May cause transient corneal injury.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2020
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
TPW