2,3,6-Trichlorophenylacetic acid

  • Acetic acid, (2,3,6-trichlorophenyl)
  • Benzeneacetic acid, 2,3,6-trichloro
  • Chlorfenac
  • Fenac
  • Fenae
  • Fenatrol
Formula
C8H5Cl3O2
Structure
Description
Crystals from benzene.
Uses
Herbicide.

Registry Numbers and Inventories.
CAS
85-34-7
EC (EINECS/ELINCS)
201-599-3
EC Index Number
607-074-00-9
EC Class
Harmful; Dangerous for the Environment
R 22 51/53
RTECS
AJ8750000
RTECS class
Agricultural Chemical and Pesticide
UN (DOT)
3077
Merck
13,2103
Beilstein/Gmelin
2113332
Beilstein Reference
4-09-00-01681
EPA OPP
82601
Swiss Giftliste 1
G-5766
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C8H5Cl3O2
Formula mass
239.48
Melting point, °C
161
Boiling point, °C
337
Vapor pressure, mmHg
2E-5
Solubility in water
200 mg/L (28 C)
pKa/pKb
3.70 (pKa)
Partition coefficient, pKow
3.20

Hazards and Protection.
Storage
Stable in storage, not harmed by freezing and thawing.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No shelf life limitations. Not harmed by freeze thaw cycles.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Fire potential
Nonflammable.

Health.
Poison_Class
4
Exposure effects
Low dose exposures - vertigo, headache, malaise, and paresthesias may occur depending on the specific compound involved. High dose exposures - muscle twitching, spasms, profound weakness, polyneuritis, and unconsciousness may occur depending on the specific compound involved. Idiosyncratic reactions - peripheral neuropathies 2,4-D and 2,4,5-T have caused adverse reproductive effects in experimental animals. Allegations of human birth defects due to these compounds have not been confirmed.
   Ingestion
Nausea, vomiting, and diarrhea have been reported. Necrosis of the gastrointestinal mucosa has been reported.
   Inhalation
Ingestion of large amounts may cause bradypnea, respiratory failure, hyperventilation, or pulmonary edema.
   Skin
Direct contact may cause skin irritation. Chlorodioxin contamination of products may produce chloracne with heavy exposure.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
3077
Response guide