2,4'-Biphenyldiamine

  • ortho,para'-bianiline
  • (1,1'-biphenyl)-2,4'-diamine
  • Ortho,Para'-diaminobiphenyl
  • 2,4'-Diaminobiphenyl
  • 2,4'-Diamino-1,1'-Biphenyl
  • 2,4'-Diaminodiphenyl
Formula
C12H12N2
Structure
Description
Needles from dil alcohol.
Uses
Detection agent for tungsten as tungstate, chemical intermediate for azo dyes.

Registry Numbers and Inventories.
CAS
492-17-1
RTECS
DV2100000
RTECS class
Tumorigen; Mutagen
UN (DOT)
3259
Merck
12,1277
Beilstein/Gmelin
2090325
Beilstein Reference
4-13-00-00360
Korea ECL
Listed

Properties.
Formula
C12H12N2
Formula mass
184.24
Melting point, °C
54
Boiling point, °C
363
Vapor pressure, mmHg
2E-5 (25 C)
Solubility in water
Slightly soluble
pKa/pKb
9.52 (pKb)
Partition coefficient, pKow
1.48
Heat of vaporization
60.9 kJ/mol
Heat of combustion
-6543 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
No data.

Fire.
Flash Point,°C
201
Fire fighting
Extinguish using agent most appropriate for surrounding fire.
Fire potential
See diphenylamine. Slight risk when exposed to heat or flame. Diphenylamine
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
CNS effects include headache, dizziness, altered mental status, confusion (lethargy progressing coma), seizures, syncope; occur secondary to CNS hypoxia, usually with levels > 20%.
   Ingestion
Nausea and vomiting may occur.
   Inhalation
Dyspnea and tachypnea may occur.
   Skin
Central cyanosis unresponsive to oxygen therapy is classic.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Emesis: ipecac-induced vomiting is not recommended because of the potential for cns depression and seizures. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Oxygen - administer oxygen to all cyanotic or symptomatic patients. Methemoglobinemia: administer 1 to 2 mg/kg of 1% methylene blue slowly iv in symptomatic patients. Additional doses may be required. Shock and cardiac arrest - treat routinely. Adjunctive therapy - exchange transfusions and hyperbaric oxygen may be useful in severe cases.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.
   Eyes
Immediately flush with running water for at least 20 minutes.

Transport.
UN number
3259
Response guide
Hazard class
8
Packing Group
I; II; III
 
9. Aromatic amines